Code of Federal Regulations (alpha)

CFR /  Title 21  /  Part 520  /  Sec. 520.2158 Streptomycin.

(a) Specifications. Each milliliter of solution contains 250 milligrams (25 percent) streptomycin sulfate.

(b) Sponsor. See Nos. 016592 and 055462 in Sec. 510.600(c) of this chapter.

(c) Related tolerances. See Sec. 556.610 of this chapter.

(d) Conditions of use. Use in drinking water as follows:

(1) Calves and swine--(i) Amount. 10 to 15 milligrams per pound (mg/pound) of body weight (1.0 to 1.5 grams per gallon).

(i) Amount. 10 to 15 milligrams per pound (mg/pound) of body weight (1.0 to 1.5 grams per gallon).

(ii) Indications for use. Treatment of bacterial enteritis caused by Escherichia coli and Salmonella spp. susceptible to streptomycin.

(iii) Limitations. Calves: Do not administer for more than 5 days. Swine: Do not administer for more than 4 days. Prepare fresh solution daily. Calves: Withdraw 2 days before slaughter. As sole source of streptomycin. Warning: Certain strains of bacteria may develop a tolerance for streptomycin. Consult a veterinarian or animal pathologist for diagnosis.

(2) Chickens--(i) Amount. 10 to 15 mg/pound of body weight (0.6 to 0.9 grams per gallon).

(i) Amount. 10 to 15 mg/pound of body weight (0.6 to 0.9 grams per gallon).

(ii) Indications for use. Treatment of nonspecific infectious enteritis caused by organisms susceptible to streptomycin.

(iii) Limitations. Chickens: Do not administer for more than 5 days. Withdraw 4 days before slaughter. Do not administer to chickens producing eggs for human consumption. Prepare fresh solution daily. As sole source of streptomycin. Warning: Certain strains of bacteria may develop a tolerance for streptomycin. Consult a veterinarian or animal pathologist for diagnosis. [57 FR 37327, Aug. 18, 1992, as amended at 58 FR 47211, Sept. 8, 1993; 63 FR 51821, Sept. 29, 1998. Redesignated and amended at 79 FR 28828, May 20, 2014; 79 FR 74020, Dec. 15, 2014]