Code of Federal Regulations (alpha)

CFR /  Title 21  /  Part 522  /  Sec. 522.2444 Thiopental injectable dosage forms. Sec. 522.2444a Thiopental powder for injection.

(a) Specifications. The drug contains sodium thiopental powder for constitution with sterile water for injection.

(b) Sponsor. See No. 054771 in Sec. 510.600(c) of this chapter.

(c) Conditions of use in dogs and cats--(1) Amount. Administer by intravenous injection as follows:

(1) Amount. Administer by intravenous injection as follows:

(i) 6 to 9 milligrams (mg) per pound of body weight for brief anesthesia (6 to 10 minutes).

(ii) 10 to 12 mg per pound of body weight for anesthesia of 15 to 25 minutes duration.

(2) Indications for use. It is used as an anesthetic for intravenous administration to dogs and cats during short to moderately long surgical and other procedures. It is also used to induce anesthesia in dogs and cats which then have surgical anesthesia maintained by use of a volatile anesthetic.

(3) Limitations. Federal law restricts this drug to use by or on the order of a licensed veterinarian. [79 FR 16196, Mar. 25, 2014] Sec. 522.2444b Thiopental and pentobarbital powder for injection.

(a) Specifications. Each gram of powder contains 750 milligrams (mg) of sodium thiopental and 250 mg of sodium pentobarbital powder for dilution with sterile water for injection.

(b) Sponsor. See No. 061623 in Sec. 510.600(c) of this chapter.

(c) Conditions of use--(1) Amount. For total anesthesia, it is given at approximately 10 to 12 mg per pound of body weight over a period of 3.5 to 5 minutes. When preanesthetic medication is used, wait at least an hour before administering thiopental and sodium pentobarbital for injection, and the dosage necessary for anesthesia is reduced. Usually \1/2\ to \2/3\ the normal amount is adequate.

(1) Amount. For total anesthesia, it is given at approximately 10 to 12 mg per pound of body weight over a period of 3.5 to 5 minutes. When preanesthetic medication is used, wait at least an hour before administering thiopental and sodium pentobarbital for injection, and the dosage necessary for anesthesia is reduced. Usually \1/2\ to \2/3\ the normal amount is adequate.

(2) Indications for use. It is used as an anesthetic for intravenous administration to dogs and cats during short to moderately long surgical procedures.

(3) Limitations. Federal law restricts this drug to use by or on the order of a licensed veterinarian. [79 FR 16197, Mar. 25, 2014]