(a) Specifications. Each dose contains cloxacillin benzathine equivalent to 500 milligrams of cloxacillin.
(b) Related tolerances. See Sec. 556.165 of this chapter.
(c) Sponsor. See No. 000010 in Sec. 510.600(c) of this chapter for use in dairy cows.
(1) Amount. Administer aseptically into each quarter immediately after last milking.
(2) Indications for use. For the treatment of mastitis caused by Staphylococcus aureus and Streptococcus agalactiae including penicillin resistant strains in dairy cows during the dry period.
(3) Limitations. For use in dry cows only. Not to be used within 30 days of calving. Animals infused with this product must not be slaughtered for food use for 30 days after the latest infusion. Federal law restricts this drug to use by or on the order of a licensed veterinarian. [57 FR 37334, Aug. 18, 1992; 57 FR 42623, Sept. 15, 1992, as amended at 60 FR 55660, Nov. 2, 1995; 75 FR 10168, Mar. 5, 2010; 75 FR 71017, Nov. 22, 2010; 79 FR 10973, Feb. 27, 2014] Sec. 526.464b Cloxacillin benzathine for intramammary infusion, sterile.
(a) Specifications. Each 6 milliliter dose contains cloxacillin benzathine equivalent to 500 milligrams of cloxacillin.
(b) Related tolerances. See Sec. 556.165 of this chapter.
(c) Sponsor. See No. 055529 in Sec. 510.600(c) of this chapter.
(1) Amount. 6 milliliters per infected quarter aseptically immediately after last milking at the time of drying-off of the cow.
(2) Indications for use. Treatment of mastitis caused by Staphylococcus aureus and Streptococus agalactiae in dairy cows at the time of drying-off of the cow.
(3) Limitations. For use in dry cows only. Not to be used within 30 days of calving. Milk taken from treated cows prior to 72 hours (6 milkings) after calving must not be used for human food. Animals infused with this product must not be slaughtered for food from the time of infusion until 72 hours after calving. Federal law restricts this drug to use by or on the order of a licensed veterinarian.
(d) Sponsor. See No. 000061 in Sec. 510.600(c) of this chapter.
(1) Amount. One dose per infected quarter immediately after last milking.
(2) Indications for use. Treatment and prophylaxis of bovine mastitis in nonlactating cows due to Streptococcus agalactiae and Staphylococcus aureus.
(3) Limitations. For use in dry cows only. Not to be used within 4 weeks (28 days) of calving. Animals infused with this product must not be slaughtered for food use for 4 weeks (28 days) after the latest infusion. Federal law restricts this drug to use by or on the order of a licensed veterinarian. [57 FR 37334, Aug. 18, 1992; 57 FR 42623, Sept. 15, 1992, as amended at 58 FR 61016, Nov. 19, 1993; 60 FR 55660, Nov. 2, 1995; 68 FR 44878, July 31, 2003] Sec. 526.464c Cloxacillin sodium for intramammary infusion, sterile.
(a) Specifications. Each milliliter contains cloxacillin sodium equivalent to 20.0 milligrams of cloxacillin.
(b) Sponsor. See No. 000061 in Sec. 510.600(c) of this chapter.
(c) Related tolerances. See Sec. 556.165 of this chapter.
(d) Conditions of use. Lactating cows--(1) Amount. 10 milliliters (one dose of 200 milligrams) per infected quarter.
(1) Amount. 10 milliliters (one dose of 200 milligrams) per infected quarter.
(2) Indications for use. Treatment of mastitis in lactating cows due to Streptococcus agalactiae and Staphylococcus aureus, nonpenicillinase-producing strains.
(3) Limitations. Administer after milking, cleaning, and disinfecting, and as early as possible after detection. Treatment should be repeated at 12-hour intervals for a total of three doses. Milk taken from treated animals within 48 hours (four milkings) after the latest treatment should not be used for food. Treated animals should not be slaughtered for food within 10 days after the latest treatment. Federal law restricts this drug to use by or on the order of a licensed veterinarian. [57 FR 37335, Aug. 18, 1992, as amended at 60 FR 55660, Nov. 2, 1995; 68 FR 44878, July 31, 2003]