Code of Federal Regulations (alpha)

CFR /  Title 21  /  Part 558  /  Sec. 558.305 Laidlomycin.

(a) Specifications. Type A medicated articles containing 50 grams laidlomycin propionate potassium per pound.

(b) Approvals. See No. 054771 in Sec. 510.600(c) of this chapter.

(c) Tolerances. See Sec. 556.346 of this chapter.

(d) Special considerations. (1) Laidlomycin liquid Type B feeds may be manufactured from dry laidlomycin Type A articles. The liquid Type B feeds must have a pH of 6.0 to 8.0, dry matter of 62 to 75 percent, and bear appropriate mixing directions as follows:

(1) Laidlomycin liquid Type B feeds may be manufactured from dry laidlomycin Type A articles. The liquid Type B feeds must have a pH of 6.0 to 8.0, dry matter of 62 to 75 percent, and bear appropriate mixing directions as follows:

(i) For liquid feeds stored in recirculating tank systems: Recirculate immediately prior to use for no less than 10 minutes, moving not less than 1 percent of the tank contents per minute from the bottom of the tank to the top. Recirculate daily as described even when not used.

(ii) For liquid feeds stored in mechanical, air, or other agitation type tank systems: Agitate immediately prior to use for not less than 10 minutes, creating a turbulence at the bottom of the tank that is visible at the top. Agitate daily as described even when not used.

(2) The expiration date for the liquid Type B feed is 21 days after date of manufacture. The expiration date for the dry Type C feed made from the liquid Type B feed is 7 days after date of manufacture.

(3) Labeling for all Type B feeds (liquid and dry) and Type C feeds containing laidlomycin shall bear the following statements:

(i) Do not allow horses or other equines access to feeds containing laidlomycin propionate potassium.

(ii) The safety of laidlomycin propionate potassium in unapproved species has not been established.

(iii) Not for use in animals intended for breeding.

(e) Conditions of use. It is used in cattle being fed in confinement for slaughter as follows: ----------------------------------------------------------------------------------------------------------------

Combination in grams

(1) 5............................ .................... For improved feed Feed continuously 054771

efficiency and in a Type C feed

increased rate of at a rate of 30 to

weight gain.. 75 mg/head/day..(2) 5............................ Chlortetracycline10 For improved feed Feed continuously 054771

mg/lb body weight. efficiency and at a rate of 30 to

increased rate of 75 mg laidlomycin

weight gain; and for propionate

treatment of bacterial potassium per head

enteritis caused by per day for not

Echerichia coli and more than 5 days.

bacterial pneumonia A withdrawal

caused by Pasteurella period has not

multocida organisms been established

susceptible to for this product

chlortetracycline.. in pre-ruminating

calves. Do not use

in calves to be

processed for

veal..(3) 5............................ Chlortetracycline For improved feed Feed continuously 054771

350 mg/head/day. efficiency and at a rate of 30 to

increased rate of 75 mg laidlomycin

weight gain; and for propionate

control of bacterial potassium per head

pneumonia associated per day. A

with shipping fever withdrawal period

complex caused by has not been

Pasteurella spp. established for

susceptible to this product in

chlortetracycline.. pre-ruminating

calves. Do not use

in calves to be

processed for

veal..(4) 5 to 10...................... .................... For improved feed Feed continuously 054771

efficiency.. in a Type C feed

at a rate of 30 to

150 milligrams/

head/day..(5) 5 to 10...................... Chlortetracycline 10 For improved feed Feed continuously 054771

mg/pound body efficiency; and for at a rate of 30 to

weight. treatment of bacterial 150 mg laidlomycin

enteritis caused by E. propionate

coli and bacterial potassium per head

pneumonia caused by P. per day for not

multocida organisms more than 5 days.

susceptible to A withdrawal

chlortetracycline.. period has not

been established

for this product

in pre-ruminating

calves. Do not use

in calves to be

processed for

veal..

(6) 5 to 10...................... Chlortetracycline For improved feed Feed continuously 054771

350 mg/head/day. efficiency; and for at a rate of 30 to

control of bacterial 150 mg laidlomycin

pneumonia associated propionate

with shipping fever potassium per head

complex caused by per day. A

Pasteurella spp. withdrawal period

susceptible to has not been

chlortetracycline.. established for

this product in

pre-ruminating

calves. Do not use

in calves to be

processed for

veal..---------------------------------------------------------------------------------------------------------------- [59 FR 18297, Apr. 18, 1994, as amended at 60 FR 53509, Oct. 16, 1995; 62 FR 9929, Mar. 5, 1997; 63 FR 27845, May 21, 1998; 66 FR 46706, Sept. 7, 2001; 68 FR 13839, Mar. 21, 2003; 68 FR 42590, July 18, 2003; 69 FR 30198, May 27, 2004; 79 FR 13545, Mar. 11, 2014]