Code of Federal Regulations (alpha)

CFR /  Title 21  /  Part 558  /  Sec. 558.612 Tiamulin.

(a) Specifications. Type A article containing 363.2 grams of tiamulin hydrogen fumarate per pound.

(b) Approvals. See No. 058198 in Sec. 510.600(c) of this chapter.

(c) Related tolerances. See Sec. 556.732 of this chapter.

(d) Special considerations--(1) Swine being treated with tiamulin should not have access to feeds containing polyether ionophores (e.g., lasalocid, monensin, narasin, salinomycin, or semduramycin) as adverse reactions may occur. If signs of toxicity occur, discontinue use.

(1) Swine being treated with tiamulin should not have access to feeds containing polyether ionophores (e.g., lasalocid, monensin, narasin, salinomycin, or semduramycin) as adverse reactions may occur. If signs of toxicity occur, discontinue use.

(2) The effects of tiamulin on swine reproductive performance, pregnancy, and lactation have not been determined.

(3) Use as sole source of tiamulin.

(e) Conditions of use--(1) Swine. It is used as follows: ----------------------------------------------------------------------------------------------------------------

Tiamulin hydrogen fumarate in Combination in grams

(i) [Reserved]................... .................... ....................... ...................(ii) 35.......................... .................... 1. For control of swine Feed continuously 058198

dysentery associated as sole ration on

with Brachyspira premises with a

(formerly Serpulina or history of swine

Treponema) dysentery but

hyodysenteriae where signs of

susceptible to disease have not

tiamulin. yet occurred or

following approved

treatment of

disease. Withdraw

2 days before

slaughter.

.................... 2. For control of Feed continuously 058198

porcine proliferative as the sole ration

enteropathies for not less than

(ileitis) associated 10 days. Withdraw

with Lawsonia 2 days before

intracellularis. slaughter.(iii) 35......................... Chlortetracycline, For treatment of swine Feed continuously 058198,

approximately 400 bacterial enteritis as sole ration for 069254

(varying with body caused by Escherichia 14 days. Use as

weight and feed coli and Salmonella only source of

consumption to choleraesuis and chlortetracycline.

provide 10 bacterial pneumonia Withdraw 2 days

milligrams of caused by Pasteurella before slaughter.

chlortetracycline multocida sensitive to As

per pound of body chlortetracycline, and chlortetracycline

weight daily). control of swine calcium complex,

dysentery associated Type A medicated

with Brachyspira articles

(formerly Serpulina or containing the

Treponema) equivalent of 50

hyodysenteriae to 100 grams per

sensitiveto tiamulin. pound of

chlortetracycline

hydrochloride

provided by 054771

and 069254 in Sec.

510.600(c) of

this chapter. Use

as only source of

tiamulin.(iv) 200......................... .................... For treatment of swine Feed continuously 058198

dysentery associated as the sole feed

with Brachyspira for 14 consecutive

(formerly Serpulina or days. Withdraw

Treponema) feed 7 days before

hyodysenteriae slaughter.

susceptible to

tiamulin.----------------------------------------------------------------------------------------------------------------

(2) [Reserved] [67 FR 7268, Feb. 19, 2002, as amended at 69 FR 62407, Oct. 26, 2004; 70 FR 75018, Dec. 19, 2005; 74 FR 6, Jan. 2, 2009; 77 FR 24139, Apr. 23, 2012; 79 FR 13546, Mar. 11, 2014. Redesignated and amended at 80 FR 13232, Mar. 13, 2015]